trouble maker

基本解释

But the teacher knows he's a trouble maker and that he doesn't know the answer, so she calls on Jim.
老师知道他是个捣蛋鬼肯定不知道答案，所以她叫了吉姆。
John has always been a trouble maker at school but when he set fire to someone's locker, it was the last straw and he was expelled.
约翰在旱校总是制造麻烦，当他对某人的橱柜放火时，实在让人忍无可忍，所以他被开除了。
edu.sina.com.cn
The A receptor is generally considered a trouble maker that interferes with sodium excretion, constricts blood vessels and promotes inflammation.
受体普遍认为是麻烦制造者，与干扰钠排泄、收缩血管和促进炎症有关。

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If you refer to someone as a troublemaker, you mean that they cause unpleasantness, quarrels, or fights, especially by encouraging people to oppose authority.